Tian Yi Zhang, MD PhD

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Tian Yi Zhang, MD PhD is an Assistant Professor of Medicine and a board-certified hematologist at Stanford University School of Medicine and Stanford Cancer Institute. Dr. Zhang also holds a PhD in Cellular and Molecular Immunology.

In her clinical practice, she treats patients with all forms of myeloid derived hematological malignancies, offering specialized expertise in acute myeloid leukemia, myelodysplastic syndrome and clonal hematopoiesis, including therapy-related myeloid neoplasms. For each patient, she develops a personalized care plan encompassing novel treatment options.

Her clinical research activities include conducting 1) both interventional and observational investigator initiated clinical trials; 2) company-sponsored early phase clinical trials evaluating the safety and efficacy of AML therapy.

The research focus of the Zhang Lab include: 1) how the immune repertoire and their functions become dysregulated in patients with myeloid malignancies; 2) how tumor-associated circulating cell-free DNA (cfDNA) can be used to track measurable residual disease (MRD) in AML; 3) cholesterol metabolic dependencies of acute myeloid leukemia (AML).

Her current and past honors include the National Cancer Institute Career Development (K08) Award, the American Society of Hematology (ASH) Research Training Award for Fellows, Stanford Cancer Institute - American Cancer Society (SCI-ACS) Pilot Grant, the A.P. Giannini Fellowship Award and Best ASH Abstract Award two years in a row. She also has earned recognition from the National Institutes of Health and American College of Physicians.

She has published her research findings on topics such as advanced therapy for high-risk myelodysplastic syndromes and reversal of bone marrow failure induced by AML. Her work has appeared in Leukemia & Lymphoma, Science Translational Medicine, Cancer Research, the Journal of Clinical Investigation, Journal of Immunology, and elsewhere.

Dr. Zhang is a member of the American Association of Cancer Research and American Society of Hematology. She advises and mentors Stanford medical students, residents and fellows. She delivers invited lectures to faculty and fellows. In addition, she has been an invited speaker on the topic of acute myeloid leukemia at the Association of Northern California Oncologists Update on Hematological Malignancies.